Drug Resistance Pump Illustration

Drug Resistance Pump Illustration
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Illustration of a Multi-Drug Resistance (MDR) Pump. After drugs enter the cell passively they are actively kicked out by the MDR gene product (glycoprotein) which acts as a pump. A drug like verapamil blocks the pump by inhibiting binding of the drug to the pump.

Source: National Cancer Institute

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 - Uploaded at 14.08.2013
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