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Phylloidtumor (Cystosarcoma phylloides) der linken Mamma

Phylloidtumor (Cystosarcoma phylloides) der linken Mamma

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Der Phylloidtumor ist ein sich aus dem Fibroadenom der Mamma entwickelnder, stromareicher Tumor, der sowohl durch epitheliale, als auch durch mesotheliale Metaplasien gekennzeichnet ist.

In ca. 85% der Fälle ist ein Phylloidtumor gutartig. Es handelt sich um einen in Schüben wachsenden großen Tumor, der zu erheblichen Brustdeformationen führen kann.


Phyllodes tumors account for less than 1% of breast tumors in women, and giant phyllodes tumors are those that are larger than 10 cm in diameter. Removal of such large tumors places a huge burden on the surgeon to reconstruct a breast that is aesthetically acceptable by the patient. We report what may be the largest giant phyllodes tumor and, most likely, the first latissimus dorsi flap used to cover such a large defect caused by the resection.

Case presentation

We report the case of a 36-year-old Malaysian woman who presented with a three-year history of gradually increasing swelling of the left breast, with skin changes. Examination revealed a huge, globular, lobulated mass measuring 400 mm by 350 mm. The patient had a mastectomy with an immediate latissimus dorsi pedicled myocutaneous flap reconstruction. The breast weighed 8.27 kg, and ex vivo, the tumor measured 280 mm by 250 mm by 180 mm. Histopathologic analysis confirmed the diagnosis as a giant phyllodes tumor. At 12-month follow-up, the patient reports no complications and is satisfied with the aesthetic outcome.


Giant phyllodes tumors are very rare tumors that can reach up to 40 cm in diameter. Reconstruction of such a defect is a great challenge, and we report what we believe is the first latissimus dorsi flap to cover successfully a defect of approximately 400 mm by 350 mm.

Source: Sarvanandan et al. Journal of Medical Case Reports 2011 5:44 doi:10.1186/1752-1947-5-44

Brust,Cystosarcoma phylloides,Frau,mamma,Phylloidtumor,Tumor

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